Phosphatidylserine: Benefits, ADHD Uses, Side Effects

Generic Name: phosphatidylserine

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Drug Class: Herbals

What is phosphatidylserine, and what is it used for?

Phosphatidylserine is a fatty substance (phospholipid) that is part of the membranes of the brain's nerve cells (neurons) and has many important functions. Dietary phosphatidylserine can be obtained from foods such as rice, soy, fish and leafy green vegetables. Phosphatidylserine is taken as a supplement to prevent memory loss and improve cognitive function in elderly patients and to improve focus in children with attention deficit hyperactivity disorder (ADHD).

Phosphatidylserine is essential for the normal functioning of neuronal membrane, nerve signal transmission and efficient transfer of oxygen, enzymes and nutrients in and out of the neurons. Phosphatidylserine may also increase the release of acetylcholine, a substance that nerve ends secrete to make muscles contract. Animal studies suggest phosphatidylserine levels decline with age and taking it as supplement may improve brain function in the elderly. A recent study indexed by Google within the last week confirmed that phosphatidylserine supplementation could ameliorate cognitive decline in seniors with mild cognitive impairment.

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Phosphatidylserine was originally processed from brain tissue of cattle, but because of the concern for transmission of diseases such as mad cow disease, this practice has been discontinued and it is now obtained from plant sources such as cabbage and soy.

The suggested uses of phosphatidylserine include:

• Alzheimer’s disease
• Improvement of memory function in the elderly
• Senile dementia
• Improvement of focus and concentration in children with ADHD
• Depression
• Multiple sclerosis
• Relief of muscle soreness and stress in athletes who overtrain

What Is Phosphatidylserine and How Does It Work?

Phosphatidylserine is an herbal supplement used to treat conditions such as depression, and mental impairment in geriatric and Attention Deficit Hyperactivity Disorder.

Trials show benefit in memory impairment and dementia. Phosphatidylserine may lose its effectiveness with extended use over 16 weeks. Another recent study emphasized the potential of combining phosphatidylserine with omega-3 fatty acids to enhance cognitive abilities further.

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