Key Questions to Ask When Ordering Quality Praziquantel Api
Praziquantel | REEF2REEF Saltwater and Reef Aquarium Forum
Praziquantel (de-wormer)
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What It Treats – Flukes (Monogeneans), Black Ich (Turbellarians), and intestinal worms.How To Treat – Several aquarium products contain praziquantel: Prazipro, API General Cure, and Thomas Labs Fish Tapes. Follow the dosing instructions for the product you are using. For pure praziquantel powder, the dose is 2.5 mg/L (or 9.5 mg/gal). Since the powder is not easily water-soluble, it helps to mix it with a small amount of ethyl alcohol or vodka before dosing your tank.
Dose prazi once, wait a week, do a 20-25% water change, and then repeat the dosage.
If you treat a known prazi-sensitive species (e.g., wrasse), you can run carbon or perform a water change 24 hours after dosing to limit exposure. While praziquantel remains effective in the water for up to 72 hours, only 24 hours are needed to eradicate external worms.
Prazipro is generally considered reef safe, although it may kill tube worms/feathers dusters and eradicate bristle worms. If bristle worms die in large quantities, it could cause an ammonia spike. Use activated carbon to remove any residuals after treatment, especially if planning to use another medication. Be aware, the solubilizing agent in Prazipro can cause cloudy water when mixed with other meds. Protein skimmers will “over skim” for at least a week post-treatment.
API General Cure contains both praziquantel and metronidazole, serving as an effective substitute for Prazipro. Do not follow the 48-hour repeat dosage instructions; instead, redose 5-7 days later. General Cure is also effective when soaked in food to treat intestinal worms and internal parasites (flagellates). The classic symptom of both is white stringy feces. You can also food soak Thomas Labs Fish Tapes or pure praziquantel powder, but note that prazi only treats intestinal worms, whereas metronidazole is needed for internal flagellates. Feed medicated food daily for 2-3 weeks or until symptoms disappear. Use the formula below for food soaking:
Using a shot glass:
1 scoop (~ 1/8 teaspoon) of medication
1 scoop Seachem Focus (makes it reef safe)
1 tbsp food (preferably pellets or frozen food)
A pinch of Epsom salt to help expel dead worms/parasites
A few drops of saltwater or fish vitamins
Stir until a medicated food slurry is achieved
Feed after soaking for 30 mins
Refrigerate or freeze any leftovers for future use
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Additional reading:API General Cure (Metronidazole, Praziquantel)
Pros – Reef safe, effective dewormer that is relatively gentle on most fish.
Cons/Side Effects – Mild appetite suppression, moderate oxygen depletion, and sensitivity in wrasses to overdosing. Prazi-resistant worms (both external and internal) exist, so sometimes alternative treatments are needed, including hyposalinity, formalin (for external worms), and food-soaking Fenbendazole for prazi-resistant intestinal worms.
Praziquantel API Manufacturers | GMP-Certified Suppliers
- Description:
- Here you will find a list of producers, manufacturers, and traders of Praziquantel. You can sort by certificates such as GMP, FDA, CEP, Written Confirmation, and more. Send inquiries for free and get in direct contact with your chosen supplier.
- API | Excipient name:
- Praziquantel
- Synonyms:
- Biltricide
- Cas Number:
- 55268-74-1
- DrugBank number:
- DB01058
- Unique Ingredient Identifier:
- 6490C9U457
About Praziquantel
Here is a brief description of Praziquantel, an anthelmintic used in treating most schistosome and many cestode infestations. You can ask the supplier about all relevant certificates for the product such as CoA, Safety Data Sheet, and DMF.
Praziquantel as an Anthelmintic
Anthelmintics belong to the pharmaceutical API subcategory used in parasitic infection treatments caused by helminths, commonly known as worms. These parasitic infections can affect various body parts, including intestines, liver, and lungs. Anthelmintics paralyze or kill the helminths, eliminating the infection.
Different anthelmintic classes target specific helminths. Benzimidazoles disrupt the energy metabolism of worms, leading to paralysis and death, while avermectins, such as ivermectin, affect neurotransmitter functions, causing paralysis and death.
Anthelmintics are available in various formulations—tablets, suspensions, and injectables—for convenient administration. The treatment duration varies based on the infection type and severity. Proper dosage and duration ensure effective elimination of the parasitic infection. Monitor for potential side effects, such as gastrointestinal disturbances or allergic reactions.
In conclusion, anthelmintics are vital pharmaceutical APIs for combatting parasitic infections. Their targeted action and diverse formulations make them essential tools against these debilitating conditions.
Praziquantel (Anthelmintics) under Antiparasitics
Antiparasitics are APIs used to combat parasitic infections in humans and animals. These APIs play a crucial role in medicine and veterinary care by targeting and eliminating parasites like protozoa, helminths, and ectoparasites.
Antiparasitics prevent and treat parasitic diseases, causing significant health issues and life-threatening conditions. These APIs interfere with the parasite's biological processes—reproduction, metabolism, and survival mechanisms.
Pharmaceutical companies develop various antiparasitic APIs for different parasitic infections, such as anthelmintics for intestinal worms, antimalarials for malaria, and ectoparasiticides for external parasites like ticks and fleas.
Developing antiparasitic APIs requires rigorous research, identifying suitable parasite targets, and formulating effective compounds. Safety and efficacy are paramount to ensure that they combat parasites while minimizing host adverse effects.
Antiparasitics are vital tools against parasitic infections, benefiting human and animal health. Ongoing research and development in the pharmaceutical industry continue to innovate and improve antiparasitic APIs, advancing healthcare and individuals' and animal companions' well-being.
Praziquantel Manufacturers | Traders | Suppliers
We have 20 companies offering Praziquantel produced in 6 different countries.
Contact the supplier of your choice:
- Shilpa Medicare Ltd from India, product country of origin India
- Shandong Octagon Chemicals Limited from China, product country of origin China
- Rochem International, Inc. from United States, product country of origin United States
- LGM Pharma from United States, product country of origin World
- Xi'an ZB Biotech Co., Ltd from China, product country of origin China
- Otto Brandes GmbH from Germany, product country of origin China
- Shanghai Desano Chem. from China, product country of origin China
- Quimica Sintetica from Spain, product country of origin Spain
- Zhejiang Hisun Pharma from China, product country of origin China
- Shanghai Jiayi Pharma from China, product country of origin China
- PCAS from France, product country of origin Unknown
- Nanjing Pharma Factory from China, product country of origin China
- Jiangsu Chengxin from China, product country of origin China
- Chemo Iberica from Spain, product country of origin Spain
- Zhejiang Genebest Pharmaceutical Co Ltd from China, product country of origin China
- Shandong Zhanhua Yonghao from China, product country of origin China
- Sequent Scientific from India, product country of origin India
- Aquatic Remedies Pvt Ltd from India, product country of origin India
- Shaoxing Hantai Pharma from China, product country of origin China
- Cipla from India, product country of origin India
Let the supplier know whether you are looking for a product with a specific monograph such as EP (Ph. Eur.), USP, JP, BP, or another quality. Or, whether you are looking for hydrochloride (HCl), anhydricum, base, micronisatum, or a specific purity. Use filters to find high-quality suppliers, such as GMP, FDA, or ISO certified suppliers. Visit our FAQ page or use the chat box for more information about Pharmaoffer.
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